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Structural Determinants of Solute Transport by MRP1 The MSDs contain the greatest sequence divergence within all ABC transporters, and an abundance of evidence indicates that they largely (but not exclusively) dictate transporter substrate selectivity (38–40)
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By synthesising emerging evidence, we systematically characterise how micronutrients modulate key AS pathological mechanisms (including oxidative stress, inflammatory regulation and endothelial protection), emphasising their interrelationships