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3 Oxidative posttranslational modifications of cysteines The availability of different oxidation states of thiol-sulfur allows the formation of a variety of oxidative posttranslational modifications (PTMs) on cysteines, including S-nitrosylation (or S-nitrosation, SNO), sulfhydration (SSH), disulfide bond formation (RS-SR), sulfenylation (SOH), sulfinic acid (SO 2 H), and sulfonic acid (SO 3 H) (10) ( Figure 1A )
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