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The brain predominantly relies on glucose for ATP generation, and disruptions in energy metabolism pathways—such as glycolysis, the tricarboxylic acid (TCA) cycle, or oxidative phosphorylation—can lead to neuronal dysfunction and degeneration, contributing to PD 36
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The report argues that large excise taxes on tobacco is by far the most important intersectoral policy to help achieve “50 by 50.” It also argues that nations will need to have basic public health capacities in place, like surveillance and contact tracing, to avert mortality while waiting for vaccine development and deployment in the next pandemic
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