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In addition, expression of Lyz2 (LyzM ), a marker of mature myeloid cells such as monocytes, macrophages and neutrophils 47 was significantly decreased in Cpt1b m−/− muscle (Table 1)

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Interestingly, activated NF-κB can bind directly on the Nrf2 promoter, regulating the transcription of the NRF2 gene and, in turn, stimulating antioxidant response [18] (Figure 1)