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This can be observed in the modulation of BCL2 family protein levels by ROS, as heightened pro-apoptotic BAX and BAK1 levels accompanied by a decrease in anti-apoptotic BCL2 and BCL2-like 1 (BCL2L1/BCL-XL) expression are observed in squamous cell carcinoma cells [114]

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By enhancing immune cell activity, improving lymphocyte function, and influencing the expression of immune checkpoints, selenium can contribute to a more favorable immune response against prostate cancer cells