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This reduction, combined with enrichment analysis revealing alterations in tryptophan metabolism, is consistent with growing experimental evidence showing a significant dysregulation of the tryptophan-kynurenine pathway in PD 34,35

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This randomized, controlled clinical trial supports our previous finding that higher milk intake was cross-sectionally correlated with higher brain GSH concentrations in older adults, and extends this finding by suggesting the potential for a causal relationship