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EBV-infected B-cells transition to lymphoblastoid physiology at approximately one week post-infection and begin to express latency III, comprised of six EBNA and two Latent Membrane Proteins (LMP) (18)

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Activation of Nrf2 can prevent BAPN-induced AD by impeding ROS-mediated activation of the NLRP3 inflammasome, concurrently diminishing the invasion of macrophage and production of MMPs and pro-inflammatory cytokines (166)