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7.4 Plaque instability and thrombotic complications The transition from stable disease to acute coronary events is governed by plaque instability and thrombus formation

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In rats, daily subcutaneous injections with 100 mg RRR-αT/kg body weight for 1 week, a mode of administration that was chosen to load the liver with extremely high concentrations of αT, reduced hepatic OATP C mRNA compared with control ( Reference Traber, Labut and Leonard 45 , Reference Farley, Leonard and Labut 46 )