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It is interesting to note that although a slightly higher concentration of betanin was required, its COX-2 inhibitory effects were comparable or greater than several phenolic compounds (cyanidin-3-O-glucoside, lycopene, chlorophyll, b-carotene, and bixin) and anti-inflammatory drugs (Ibuprofen, Vioxx and Celebrex)

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Despite the large number of studies indicating that VEGF can affect multiple aspects of the wound healing process, most of the effects of VEGF during wound repair have been attributed to its proangiogenic activity