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a causal relationship has not been established, but individuals who develop severe, persistent abdominal pain with or without vomiting should stop use and seek urgent medical assessment [11] Gallbladder disease, including gallstones, is a recognised class risk Delayed gastric emptying, which may reduce the absorption of oral medicines taken at the same time Possible thyroid C-cell effects, as observed with other GLP-1 receptor agonists in animal studies