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*Major components affected in primary immune deficiency Innate immunity occurs rapidly and is relatively nonspecific, while adaptive responses occur later and are characterized by activation of the T and B lymphocytes, antigen recognition, cognate interaction using several key cell surface receptors (discussed later) and the synthesis and secretion of antibodies, cytokines and other effector molecules that lead to an expansion of the specific immune response towards a pathogen (Table 2)
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Independentemente do objetivo, vários princípios prudentes são recorrentes: começar pela dose mais baixa eficaz relatada, observar a resposta individual, manter consistência na qualidade do produto e na técnica de reconstituição, e evitar aumentar a dose sem necessidade
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