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Upon detecting ATO-induced hepatotoxicity, intravenous infusion of MgIG (Wang et al., 2019) (200 mg/day for at least 2 weeks) or oral bicyclol (Tang et al., 2022) (25 or 50 mg TID for 2–4 weeks) can be initiated

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Intramuscular injection is technically more demanding and carries greater risk than the subcutaneous route, so it should only be undertaken with proper training and a clear anatomical understanding of the chosen site

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