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This difference likely indicates that cystine starvation constitutes a more severe perturbation of cellular cysteine homeostasis than pharmacological inhibition of system x c - by erastin2 or glutamate, leading to a more rapid and extensive depletion of the intracellular cysteine pool

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Laboratory research record on Cagrilintide [PMID: 42228334] PubMed laboratory record discussing Cagrilintide in a research context