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Histological examination showed that melanocytes survived and successfully integrated into the basal layer of the epidermis, indicating that the combination of microneedles and melanocyte transplantation could be a viable strategy for patients with vitiligo who do not respond well to traditional treatments.In conclusion, microneedle therapy, as an innovative drug delivery technique, utilizes fine needle-like devices to create microinjuries or stimuli on the skin and can deliver therapeutic drugs simultaneously or stepwise, improving transdermal absorption efficiency and therapeutic efficacy

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& Mastrocola, R