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Whether isopentylation impacts GPX4 levels to an extent that would affect ferroptosis sensitivity remains to be directly tested 124

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Detection Type:Chromogenic (Clear Plates)

The His230 residue in catalytic pocket of pytH deprotonates hydroxyl group of Ser78, which in turn performs nucleophilic attack on carbonyl carbon of the pyrethroid’s ester bond (Xu et al., 2020)