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More importantly, TB500 can help to improve both natural and synthetic antibiotic penetration into tissue, resulting in higher concentrations of antimicrobials in the very areas where they are needed

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For example, oleic acid (OA) can cause lipid accumulation in hepatocytes and their apoptosis by inducing mitochondrial membrane dysfunction and upregulating death receptor 5, the ligand of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) [84, 85]