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Initial assessment in rats with two ligations at the left colic artery and vein for 15 min (IC rats) and in rats that had two ligations at the left colic artery and vein for 15 min, and then were reperfused for the next 15 min (IC + RL rats) The surgery was conducted in deeply anesthetized rats

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Epithelial cells were further classified into 18,642 tumor cells and 5239 normal cells using the InferCNV algorithm