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Likewise, several studies have reported the advantages of combining matrine with irinotecan and cisplatin to augment their antitumor activity against human colorectal (HT29) (419), urothelial bladder (EJ and T24) (420), liver (HepG2) (421), and cervical (U14) (422) cancer cell lines

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In one cross-sectional study of healthy adults, total white blood cell (WBC) counts (including lymphocytes and neutrophils) fell significantly by the third week of Ramadan compared to pre-Ramadan values, though importantly all counts remained within normal physiological ranges