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6H), markedly weaker than the synergistic interaction observed in MOLM-13 cells, suggesting that healthy cells lack the specific redox and signalling susceptibilities that are exploited in drug cooperation and further supporting the conclusion that treatment with these compounds will specifically target cancerous cells with minimal impact on HSCs

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Alternative markers such as cystatin C-based eGFR or enzymatic creatinine assays may provide more accurate assessment when clinical concern exists, as recommended in KDIGO guidelines