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The complexity of early-life immune priming is further illuminated by mouse models where pathological traits resulting from prenatal immune activation, such as reduced sociability and elevated cued fear, were observed to persist across multiple generations

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That said, the homooligomeric ThDP-dependent enzymes participating in metabolism of glucose and amino acids, i.e., TKT, OGDH, DHTKD1, preserve their cluster partners in both of the studied experiments