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Inflammatory disorders Severe infectious keratitis induces anterior subcapsular, pyramidal or total lens opacities Chronic iridocyclitis produces anterior subcapsular opacities, especially in the iris-lens synechiae Fuchs’ heterochromic iridocyclitis involves the following ocular changes chronic cyclitis with corneal endothelial precipitates, without iris-lens synechiae heterochromia iridis (color difference between the two eyes due to iris atrophy in the affected eye, which appears more discolored) early unilateral cataract with posterior cortical onset and slow progression to total cataract uveitis Degenerative disorders Hereditary retinal dystrophies (retinopathy pigmentosa, gyrate atrophy, Leber congenital amaurosis, etc.) and progressive iris atrophy High myopia is frequently associated with posterior subcapsular or nuclear cataract Intraocular tumors Retinal detachment Glaucoma Acute glaucoma leads to the formation of anterior subcapsular opacities (glaucomflecken) in the pupillary area

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