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Iron sorbitol citrate Routes of Administration • Intravenous (IV) – most commonly used • Intramuscular (IM) – less commonly used because it may cause pain and staining of the skin Indications Parenteral iron is used when: • Severe iron deficiency anemia • Oral iron intolerance (vomiting, severe gastric irritation) • Malabsorption disorders (e.g., celiac disease) • Chronic kidney disease • Need for rapid correction of anemia • Non-compliance with oral iron • Inflammatory bowel disease Advantages • Rapid replenishment of iron stores • Useful when oral therapy fails • Better absorption than oral iron Disadvantages / Side Effects • Pain at injection site • Skin staining (with IM injection) • Nausea and headache • Fever and joint pain • Hypotension • Allergic or anaphylactic reactions (rare but serious) Nursing Considerations • Perform test dose especially with iron dextran • Monitor patient for allergic reactions • Use Z-track technique for IM injections to prevent staining • Monitor hemoglobin and hematocrit levels • Keep emergency drugs ready in case of anaphylaxis Examples of Conditions Treated • Iron deficiency anemia in pregnancy • Chronic kidney disease anemia • Post-partum anemia Parenteral Iron Treatment for Iron Deficiency Anemia Parenteral iron refers to iron given by injection (intravenous or intramuscular) instead of by mouth to treat iron deficiency anemia when oral iron cannot be used or is ineffective
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