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However, these factors alone cannot explain epidemiological studies showing that each new generation carries a slightly higher risk of breast cancer than the prior one 2,8,9,10,11

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NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ mice [NOD scid gamma (NSG™)] mice (Jackson Laboratory) aged 8-11 weeks (20-30 g) were used in the present study with food and water at ad libitum (n=18)