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Select Drug-Drug Interactions With Direct Oral Anticoagulants: JACC Review Topic of the Week - ScienceDirect
7 However, challenges remain, including achieving selectivity, determining optimal ROS thresholds, distinguishing ROS levels in healthy versus cancer cells, and bridging preclinical and clinical studies
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By enabling experimental perturbation of spatially defined macrophage–stromal interactions, these platforms provide functional validation of pathogenic niches first identified by spatial omics, thereby bridging discovery-phase diagnostics with therapeutic testing
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