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However, even the lower bound of the prevalence estimate of 5% is significant, as mitochondrial disease is only believed to affect T polymorphism and behaviors in children with autism: exploratory genotype-phenotype correlations

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This knowledge coupled with the demonstration that some members of the 6-AH family bound with high affi nity to the hinge region of HGF led to the expectation that other active AnglV analogs, like 6-AH family members, could be expected to inhibit HGF dimerization and that the ability of an individual analog to bind HGF and inhibit HGF-dependent processes should be reflected in its capacity to attenuate dimerization